About Me
I am a former PhD student at the group of Modeling and Simulation.
Publications
- A. Andreychenko, L. Mikeev, V. Wolf: Model Reconstruction for Moment-Based Stochastic Chemical Kinetics. ACM Trans. Model. Comput. Simul. 25(2): 12:1-12:19 (2015)
- C. Bock, L. Bortolussi, T. Krüger, L. Mikeev, V. Wolf: Model-Based Whole-Genome Analysis of DNA Methylation Fidelity. HSB 2015: 141-155 2013
- L. Mikeev, Martin R. Neuhäußer, D. Spieler, V. Wolf: On-the-fly verification and optimization of DTA-properties for large Markov chains. Formal Methods in System Design 43(2): 313-337 (2013)
- L. Mikeev, W. Sandmann, V. Wolf: Numerical Approximation of Rare Event Probabilities in Biochemically Reacting Systems. CMSB 2013: 5-18 2012
- A. Andreychenko, L. Mikeev, D. Spieler, V. Wolf: Approximate maximum likelihood estimation for stochastic chemical kinetics. EURASIP J. Bioinformatics and Systems Biology 2012: 9 (2012)
- L. Mikeev, V. Wolf: Parameter estimation for stochastic hybrid models of biochemical reaction networks. HSCC 2012: 155-166 2011
- A. Andreychenko, L. Mikeev, D. Spieler, V. Wolf: Parameter Identification for Markov Models of Biochemical Reactions. CAV 2011: 83-98
- M. Lapin, L. Mikeev, V. Wolf: SHAVE: stochastic hybrid analysis of markov population models. HSCC 2011: 311-312
- L. Mikeev, W. Sandmann, V. Wolf: Efficient calculation of rare event probabilities in Markovian queueing networks. VALUETOOLS 2011: 186-196
- A. Andreychenko, L. Mikeev, D. Spieler, V. Wolf: Parameter Identification for Markov Models of Biochemical Reactions. CoRR abs/1102.2819 (2011) 2010
- T. A. Henzinger, L. Mikeev, M. Mateescu, V. Wolf: Hybrid numerical solution of the chemical master equation. CMSB 2010: 55-65
- T. Dayar, L. Mikeev, V. Wolf: On the Numerical Analysis of Stochastic Lotka-Volterra Models. IMCSIT 2010: 289-296
- T. A. Henzinger, M. Mateescu, L. Mikeev, V. Wolf: Hybrid Numerical Solution of the Chemical Master Equation. CoRR abs/1005.0747 (2010)
Interests
- Numerical analysis of large structured Markov chains
- Computation of rare event probabilities
- Fokker-Planck approximation of the chemical master equation
Publications (10)
2015
Model-Based Whole-Genome Analysis of DNA Methylation Fidelity
2015 — Hybrid Systems Biology - Fourth International Workshop. Revised Selected Papers. International Conference on Hybrid Systems Biology (HSB-2015), September 4-5, Madrid, Spain
Model Reconstruction for Moment-Based Stochastic Chemical Kinetics
2015 — ACM Transactions on Modeling and Computer Simulation (TOMACS)
2013
On-the-fly verification and optimization of DTA-properties for large Markov chains
2013 — Formal Methods in System Design
Numerical Approximation of Rare Event Probabilities in Biochemically Reacting Systems
2013 — Computational Methods in Systems Biology. International Conference on Computational Methods in Systems Biology (CMSB-2013), 11th International Conference, CMSB 2013, September 22-24, Klosterneuburg, Austria
2012
Parameter estimation for stochastic hybrid models of biochemical reaction networks
2012 — HSCC ‘12: Proceedings of the 15th ACM international conference on Hybrid Systems: Computation and Control. ACM International Conference on Hybrid Systems: Computation and Control (HSCC-2012), April 17-19, Beijing, China
Approximate maximum likelihood estimation for stochastic chemical kinetics
2012 — EURASIP Journal on Bioinformatics and Systems Biology
2011
Efficient Calculation of Rare Event Probabilities in Markovian Queueing Networks
2011 — VALUETOOLS ‘11: Proceedings of the 5th International ICST Conference on Performance Evaluation Methodologies and Tools. International ICST Conference on Performance Evaluation Methodologies and Tools (VALUETOOLS-2011), May 16-20, Paris, France
SHAVE: stochastic hybrid analysis of markov population models
2011 — HSCC ‘11: Proceedings of the 14th international conference on Hybrid systems: computation and control. ACM International Conference on Hybrid Systems: Computation and Control (HSCC-2011), April 12-14, Chicago,, IL, USA
2010
On the numerical analysis of stochastic Lotka-Volterra models
2010 — Proceedings of the International Multiconference on Computer Science and Information Technology. Computer Aspects of Numerical Algorithms (CANA-2010), located at IMCSIT 2010, October 18-20, Wisla, Poland
Hybrid numerical solution of the chemical master equation
2010 — Proceedings of the 8th International Conference on Computational Methods in Systems Biology. International Conference on Computational Methods in Systems Biology (CMSB-2010), Proceedings of the 8th International Conference on Computational Methods in Systems Biology, September 29 - October 1, Trento, Italy