Hidden Markov Models
DNA methylation is an epigenetic mark whose important role in development has been widely recognized. This epigenetic modification …
@article{luckHiddenMarkovModellingReveals2019,
author = {Alexander Lück and Pascal Giehr and Karl Nordström and Jörn Walter and Verena Wolf},
doi = {10.1109/TCBB.2019.2910814},
journal = {IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)},
month = {4},
number = {5},
pages = {1598-1609},
publisher = {IEEE},
title = {Hidden Markov Modelling Reveals Neighborhood Dependence of Dnmt3a and 3b Activity},
volume = {16},
year = {2019}
}
DNA methylation and demethylation are opposing processes that when in balance create stable patterns of epigenetic memory. The control …
@article{giehrTheInfluenceOfHydroxylation2016,
author = {Pascal Giehr and Charalampos Kyriakopoulos and Gabriella Ficz and Verena Wolf and Jörn Walter},
doi = {10.1371/journal.pcbi.1004905},
journal = {PLOS Computational Biology},
month = {5},
number = {5},
pages = {1-16},
publisher = {Public Library of Science},
title = {The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach},
volume = {12},
year = {2016}
}
The enzymatic control of the setting and maintenance of symmetric and non-symmetric DNA methylation patterns in a particular genome …
@article{arandInVivoControlOf2012,
author = {Julia Arand and David Spieler and Tommy Karius and Miguel R. Branco and Daniela Meilinger and Alexander Meissner and Thomas Jenuwein and Guoliang Xu and Heinrich Leonhardt and Verena Wolf and Jörn Walter},
doi = {10.1371/journal.pgen.1002750},
journal = {PLOS Genetics},
month = {6},
number = {6},
pages = {1-11},
publisher = {PLOS},
title = {In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases},
url = {https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002750},
volume = {8},
year = {2012}
}