Alexander Lück

I was a PhD student at the group of Modeling and Simulation from January 2015 until August 2020.


  • A. Lück, V. Wolf: A Stochastic Automata Network Description for Spatial DNA-Methylation Models, International Conference on Measurement, Modelling and Evaluation of Computing Systems, MMB 2020
  • A. Lück, P. Giehr, K. Nordström, J. Walter, V. Wolf: Hidden Markov modelling reveals neighborhood dependence of Dnmt3a and 3b activity, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2019
  • C. Kyriakopoulos, P. Giehr, A. Lück, J. Walter, V. Wolf: A Hybrid HMM Approach for the Dynamics of DNA Methylation, International Workshop on Hybrid Systems Biology, HSB 2019
  • P. Kurasov, A. Lück, D. Mugnolo, V. Wolf: Stochastic hybrid models of gene regulatory networks – A PDE approach, Math. Biosci 305, 2018
  • C. Arita, J. Bosche, A. Lück, L. Santen: Localization of a microtubule organizing center by kinesin motors, J. Stat. Mech. 12 123210, 2017
  • A. Lück, P. Giehr, J. Walter, V. Wolf: A Stochastic Model for the Formation of Spatial Methylation Patterns, Computational Methods in Systems Biology, CMSB 2017
  • A. Lück, V. Wolf: Generalized method of moments for estimating parameters of stochastic reaction networks, BMC Syst. Biol. 10:98, 2016
  • A. Lück: Replicated computational results (RCR) report for “Automatic Moment-Closure Approximation of Spatially Distributed Collective Adaptive Systems.”, ACM Trans. Model. Comput. Simul. 26, 4, Article 27, 2016
  • C. Arita, A. Lück, L. Santen: Length regulation of microtubules by molecular motors: exact solution and density profiles, J. Stat. Mech. 6 P06027, 2015

Teaching Assistance

  • Summer Semester 2019: Lecture: Probabilistic Models and Data Analysis
  • Winter Semester 2018/19: Seminar: Probabilistic Models of Concurrency
  • Winter Semester 2017/18: Ringvorlesung: Perspektiven der Informatik
  • Winter Semester 2016/17: Lecture: Modelling and Simulation
  • Summer Semester 2016: Proseminar: Prob. Modelle und Netzwerkmodellierung
  • Winter Semester 2015/16: Ringvorlesung: Perspektiven der Informatik
  • Summer Semester 2015: Proseminar: Anwendungen stochastischer Modelle

Other work

I reviewed manuscripts for the following conferences CAV 2015, CAV 2017, CIBCB 2019, CMSB 2016, CMSB 2017, CONCUR 2018, HSB 2019, MMB&DFT 2016, and journals Applied Mathematics and Computation, BMC Bioinformatics.

Thesis co-supervision

  • A. Kupitz: Design and calibration of stochastic models for DNA methylation patterns, Master Thesis, 2019
  • A. Bies: Multi-dimensional moment-based methods for parameter inference in biochemical networks, Bachelor Thesis, 2016