Charalampos Kyriakopoulos


  • C. Kyriakopoulos, V. Wolf: Optimal Observation Time Points in Stochastic Chemical Kinetics, HSB’, CAV Proceedings 2014
  • C. Kyriakopoulos, P. Giehr, G. Fisz, V. Wolf, J. Walter: The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: a HMM approach, PLoS Computational Biology, 2016
  • M. A. Eckersley-Maslin, V. Svensson, C. Krüger, T. Stubbs, P. Giehr, F. Krüger, R. Miragaia, C. Kyriakopoulos, R. Berrens, I. Milagre, J. Walter, S. Teichmann, W. Reik: MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs, Cell Reports, 2016
  • C. Kyriakopoulos, P. Giehr, V. Wolf: H(O)TA: estimation of DNA methylation and hydroxylation levels and efficiencies from time course data, Bioinformatics, 2017
  • C. Kyriakopoulos, G. Grossmann, V. Wolf, L. Bortolussi: Lumping of Degree-Based Mean Field and Pair Approximation Equations for Multistate Contact Processes, Physical Review E, 2018
  • P. Giehr, C. Kyriakopoulos, K. Lepikhov, S. Walner, V. Wolf, J. Walter: Two are better than one: HPoxBS – Hairpin oxidative Bisulfite Sequencing, Nucleic Acids Research, 2018
  • G. Grossman, C. Kyriakopoulos, L. Bortolussi, V. Wolf: Lumping the Approximate Master Equation for Multistate Processes in Complex Networks, QEST 2018
  • C. Kyriakopoulos, P. Giehr, A. Lück, J. Walter, V. Wolf: A Hybrid HMM Approach for the Dynamics of DNA Methylation, HSB 2019
  • C. Kyriakopoulos, P. Giehr, K. Nordström, S. Abdulrahman, F. Müller, F. von Meyenn, G. Ficz, W. Reik, V. Wolf, J. Walter: Genome-wide single-base resolution efficiency profiling reveals modulation of maintenance and de novo methylation by Tet di-oxygenases, under review




  • Advanced Course WS16/17: Modeling and Simulation
  • Advanced Course WS15/16: Probabilistic Models and Data Analysis
  • Block Course SS14: Computational Modelling of Complex Networks
  • Seminar SS14: Stochastic Modelling in the Biological Sciences
  • Lecture WS13/14: Energy Informatics


I have reviewed manuscripts for ASMTA 2016, CAV 2017, CMSB 2014, CMSB 2015, CMSB 2016, CMSB 2018, CONCUR 2018, HSB 2015, HSCC 2016, QEST 2014, QEST 2016, ROCKS 2014 and Bioinformatics Journal. Moreover, I have been the co-supervisor of the Master Theses of Mayank Goyal and Gerrit Grossman.